Practice research is a meeting point between practice and research, involving collaborations and negotiations to ensure that research findings are usable for improving services and living conditions. It is still embryonic and could be challenging for novice researchers or experienced researchers without an adequate understanding. For social science researchers and practitioners who are interested in improving service delivery and shaping positive outcomes, the practice research methodology is the go-to approach. However, there is inadequate clarity about how the core theoretical foundations of practice research are represented in the methodology. In this article, we demonstrate the application of a practice research methodology to the co-production of an assessment tool for social workers in Ghana. While our case study focused on the production of knowledge within social work practice, the principles and theories of practice research are applicable to other cognate social science disciplines that aim to produce knowledge usable in practice.