The aims of the current study were to examine the temporal differences in match-running performances and heart rate (HR) in elite senior hurling players between halves of play and field positions. Global positioning systems (10 Hz) and HR monitors were used to collect data from 48 players over 18 games. Running performances (total distance [TD], relative distance, high-speed running [HSR], sprint efforts [SE], mean length of sprints, and sprint distance [SD]) and HR values (HRmean and HRpeak) were assessed. Decrements in TD (p = 0.009, effect size [ES] = −0.15), relative distance (p = 0.009, ES = −0.18), HSR (p = 0.001, ES = −0.28), SE (p = 0.001, ES = −0.23), SD (p = 0.001, ES = −0.24), HRmean (p < 0.001, ES = −0.38), and HRpeak (p < 0.001, ES = −0.21) were found between halves. Half backs showed between-half decrements in all metrics (p < 0.05) except SD (p = 0.130, ES = −0.26). Midfielders (p < 0.001, ES = −0.68) and half forwards (p < 0.001, ES = −0.79) experienced second-half decrements in HSR. No decrements (p > 0.05) in running performances were found between halves for full backs. HRmean was lower in full backs (p = 0.007, ES = −0.46) and half backs (p = 0.001, ES = −0.76) in the second half. Coaches should consider the specific HSR between-half temporal decrements in half backs, midfielders, and half forwards, and customize training program design to minimize these decrements.