Background
Motor neurone disease results in complex and disabling symptoms that give rise to significant and challenging care needs. While much of the care required is typically provided by the partner of the individual who has been diagnosed with MND, there are few studies which have investigated the impact of MND on the couple relationship.

Objectives
To establish the current state of the research literature examining the impact of MND on the couple relationship.

Methods
A scoping review was undertaken with thematic analysis used to synthesize the data.

Results
The scoping review identified fifteen studies which were thematically analysed to identify prominent themes. The following five themes were identified: adjusting to new roles; changes in communication and values; spouse wellbeing and health; changes to social relationships and intimacy changes.

Significance of results
This scoping review highlighted the impact of the MND disease trajectory on the couple relationship overall and on key areas of couple communication and functioning. These areas can be used to guide the Cambridge University Press Palliative & Supportive Care For Peer Review development of interventions and services that are tailored to the needs of couple relationships. Further understanding of the factors impacting the couple relationship on the MND journey and how to navigate these factors is critically warranted.