The concise guide to pharmacology 2023/24: ion channels

Alexander, Stephen P. H., Mathie, Alistair, Peters, John A., Veale, Emma L., Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F., Faccenda, Elena, Harding, Simon D., Davies, Jamie A., Aldrich, Richard W., Attali, Bernard, Baggetta, Austin M., Becirovic, Elvir, Biel, Martin, Bill, Roslyn M., Caceres, Ana I., Catterall, William A., Conner, Alex C., Davies, Paul, De Clerq, Katrien, Delling, Markus, Di Virgilio, Francesco, Falzoni, Simonetta, Fenske, Stefanie, Fortuny‐Gomez, Anna, Fountain, Samuel, George, Chandy, Goldstein, Steve A. N., Grimm, Christian, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Hu, Meiqin, Ijzerman, Ad P., Jabba, Sairam V., Jarvis, Mike, Jensen, Anders A., Jordt, Sven E., Kaczmarek, Leonard K., Kellenberger, Stephan, Kennedy, Charles, King, Brian, Kitchen, Philip, Liu, Qiang, Lynch, Joseph W., Meades, Jessica, Mehlfeld, Verena, Nicke, Annette, Offermanns, Stefan, Perez‐Reyes, Edward, Plant, Leigh D., Rash, Lachlan, Ren, Dejian, Salman, Mootaz M., Sieghart, Werner, Sivilotti, Lucia G., Smart, Trevor G., Snutch, Terrance P., Tian, Jinbin, Trimmer, James S., Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D., Winn, Brenda T., Wulff, Heike, Xu, Haoxing, Yang, Fan, Fang, Wei, Yue, Lixia, Zhang, Xiaoli and Zhu, Michael (2023) The concise guide to pharmacology 2023/24: ion channels. British Journal of Pharmacology, 180 (S2). pp. 145-222. ISSN 1476-5381

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The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (, which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Item Type: Article
Uncontrolled Keywords: pharmacology, ion channels
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Health & Science > Department of Health Studies
SWORD Depositor: Pub Router
Depositing User: Pub Router
Date Deposited: 04 Jan 2024 10:45
Last Modified: 04 Jan 2024 10:45

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